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Though citrulline and GAA were able to replace arginine in low-protein poultry diets and demonstrate arginine-sparing effects (Esser et al., 2017), GAA was found to be less effective in replacing arginine (Dao et al., 2021b)

However due to their mechanisms of action, it is plausible that they all could have direct or indirect beneficial effects on the male reproductive axis, mainly through the action of GLP -1 ( Figure 1 )

This was supported by a study showing that antagonism of CGRP signaling improved metabolic parameters and potentially inhibited metabolic decline in aged mice [94]

Mitochondrial Energy Production NAD+ is a central cofactor in the electron transport chain

Contains: D-Ribose 5000mg Acetyl L-carnitine 1000mg Co-enzyme Q10 300mg Magnesium Orotate 500mg