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Zonation differences are associated with phase I and phase II metabolism enzymes, with a predominant centrilobular localization of most constitutively expressed P450s (Figure 1A and 1B) and other phase I enzymes and a predominant periportal expression of most phase II enzymes

Olive leaf extract modified muscle mitochondrial responses to both moderate and sprint exercise

however, this does not necessarily mean exercise can be replaced by MOTS-c supplementation

Malondialdehyde, a byproduct of lipid peroxidation, is a marker for both ferroptosis and oxidative stress (56)

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