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observed that supplementation with LC (250 mg oral L-carnitine supplementation for 12 weeks) leads to a significant reduction in body weight, body mass index and waist and hip circumference decreasing blood glucose levels and favors the contrast of insulin resistance [73], which may be attributed to the increase in -oxidation of fatty acids and the metabolic rate base line induced by LC [74]

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Why it matters for body composition: Tesofensine not only reduces caloric intake by controlling hunger but also ramps up basal metabolic rate , making it easier to burn fat while preserving lean muscle, especially when combined with a structured strength training plan

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