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Change history 09 September 2014 This paper was modified 12 months after initial publication to switch to Creative Commons licence terms, as noted at publication References Adler V, Yin Z, Fuchs SY, Benezra M, Rosario L, Tew KD, Pincus MR, Sardana M, Henderson CJ, Wolf CR, Davis RJ, Ronai Z (1999) Regulation of JNK signaling by GSTp

To view a copy of this licence, visit About this article Cite this article Marathe, S.J., Grey, E.W., Bohm, M.S

Several peripheral and central mechanisms are believed to be involved, including altered gut hormone secretion, decrease in energy expenditure following weight loss, and psychological processes associated with the food reward system

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A weight loss intervention is typically considered successful if participants achieve more than 5-10% of weight loss