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(PubMed) Pryor WA, Houk KN, Foote CS, et al

Th1 cytokine interferon gamma improves response in HER2 breast cancer by modulating the ubiquitin proteasomal pathway

This is done by mixing an enzyme with a substrate that has deuterium atoms substituted for the hydrogens, so the enzyme will reduce NAD + by transferring deuterium rather than hydrogen

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimers disease

The study examined real-world data across seven obesity-related solid tumors, comparing patients on GLP-1 receptor agonists to those on DPP-4 inhibitors and other anti-diabetics