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R., Lu, W., Grabocka, E

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In contrast, over extended treatment durations, patients may develop drug resistance, or compensatory metabolic adaptations may gradually attenuate drug efficacy [338]

Additionally, GLP-1 has been shown to enhance the proliferation and differentiation of endothelial progenitor cells through upregulation of VEGF, potentially promoting angiogenesis that could contribute to retinal complications [101,102]

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