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Institut de Recerca de lHospital de la Santa Creu i Sant Pau (Institut de Recerca SANT PAU) is accredited by the Generalitat de Catalunya as Centre de Recerca de Catalunya (CERCA)

In blood pressure studies, NaBPC157 (without effect on basal normal values) compared with L-arginine has both a mimicking effect (impaired L-NAME-blood pressure increase, applied prophylactically and decreased already raised L-NAME values, given at the time of the maximal L-NAME-blood pressure increase (i.e., 10 minutes after L-NAME)) and a preventative activity (L-arginine-induced moderate blood pressure decrease was prevented by NaBPC157 pre-treatment)

Never share injection devices or needles with another person, even if the needle is changed

Berberine can improve various clinical outcomes (Li et al., 2023b)

Declaration The authors declare that they have not use AI-generated work in this manuscript