The recovery path is equally specific: electrolytes early, real food, shade, pacing, and time
Our data suggest that the glutathione deficiency in aged humans occurs in large part because of a markedly diminished supply of the precursors glycine and cysteine rather because of a diminished capacity to synthesize glutathione
Long-term continuous use data is limited, but occasional cycles appear safe
Reduce oxidative DNA damage markers (8-OHdG) by 20% (NIH)
While current redox proteomics in CF often focuses on identifying which proteins are modified (e.g., carbonylated, glutathionylated), techniques like FPOP offer the potential to delve deeper into how these modifications occur - identifying specific residues targeted by ROS - and how these modifications, or the oxidative environment itself, impact protein structure, dynamics, and interactions (Johnson et al., 2019