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Participants treated with liraglutide (239), semaglutide (240), or tirzepatide (200) in the clinical trials had a percent reduction in fat mass approximately three times greater than the reduction in lean mass, leading to an overall improvement in body composition

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These molecular observations were corroborated by histopathological examination, which provided direct anatomical evidence of neuroprotection

2 solution samples were respectively injected into 1H-NMR system (Bruker AM300, Bruke Corporation, Germany) 13C-NMR system (Bruker AM400, Bruke Corporation, Germany)

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