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It should be noted that these findings do not imply that DPP-4 inhibitors are harmful in any way or that GLP-1 drugs are definitely beneficial for brain health.
Am J Physiol - Regul Integr Comp Physiol (2016) 310(10):R88595
However, the work was primarily conducted by one group of researchers in Croatia
Nevertheless, although the number of patients who had a TyG index value of 8.8 (non-insulin resistance) increased significantly in both the no/low CKD risk and CKD groups after 12 months of treatment ( Figures 3A, B ), when further stratification according to CKD severity was performed, a lower proportion of patients achieving a TyG value 8.8 was reported in the subgroup of very high CKD risk ( Figures 3CE )
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