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When adjusted for changes in lean body mass and fat mass, metabolic rate remains proportional to body composition

In a phase 3 clinical trial, Zepbound led to an average weight loss of 22.5% body weight, or about 52 pounds, surpassing all currently available weight loss medications on the market

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GLP-1 receptor agonists (GLP-1RAs) like liraglutide and semaglutide, as well as the dual GLP-1 and gastric inhibitory polypeptide (GIP) agonist tirzerpatide are a class of medications that were historically designed to treat type 2 diabetes

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