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In this study, we used a computationally-guided approach to design and characterize a library of covalent fragments functionalized with a natural product-inspired 3-bromo-4,5-dihydroxazole (BDHI) electrophile

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Despite treatment, the woman is unable to verbalize or care for herself, requiring an ongoing feeding tube for nutritional support.

Once again, the committee voted 8-6 in favor of reclassifying TB-500, with one absention

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