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The A8 peptide (SPWPRPTY) blocked the interaction between Hsp72 and TLR2 and the subsequent activation of MDSCs, thereby inhibiting tumor progression and potentiating the antitumor effect of chemotherapeutic agents, such as cisplatin 115

Effect of the Pineal Gland Peptide Preparation Epithalamin on the Lifespan and Spontaneous Tumour Incidence in Female SHR Mice Mechanisms of Ageing and Development Epithalamin treatment begun in old age increased mean lifespan of female SHR mice by 12.3%, reduced spontaneous tumour incidence, and inhibited tumour growth rate extending maximum lifespan

doi: 10.1073/pnas.1103555108