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Prolonged exposure to irritants such as tobacco smoke leads to a sustained increase in oxidative stress in the lungs of COPD patients, which in turn inhibits the function of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway and weakens the bodys antioxidant defences, leading to further damage to alveolar structure, increased airway remodelling, and inflammatory responses, thus driving the pathological progression of the disease [7]

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L., Cheng, H., Huang, S., Fu, Z., Li, P., Wu, L., & Zheng, H

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Because of this steady release ipamorelin can sustain the rise in insulin-like growth factor (IGF-1) that triggers many of the anabolic benefits of growth hormone therapy