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The goal is to gradually reduce sympathetic nervous system activation and allow the parasympathetic system to take over

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All of them are not effective and many may not be suitable for certain types of weight loss journey

J Pharm Sci

These early studies confirmed the once-weekly dosing feasibility and identified the gastrointestinal side effectsprimarily nausea, vomiting, and diarrheathat would become characteristic of GLP-1 receptor agonist therapy