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After thoroughly mixing the extract by vortexing, the precipitated protein was removed by centrifugation (16,000 g , 5 min, 4 C) before the supernatants were analysed by HPLCMS

False discovery rate (FDR) control was applied using the BenjaminiHochberg method at a threshold of 0.1

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FIGURE 4 The brain-derived neurotrophic factor (BDNF) pathway is considered an important molecular link between GC signaling and LTP regulation