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Potential Side Effects of Switching From Trulicity to Ozempic It is unlikely that switching from Trulicity to Ozempic will cause any unexpected side effects (though you should contact your doctor immediately with any concerns)

A recent paper published in The Lancet showed that nearly 20% of participants in lifestyle interventions without medications gain weight, around 40% lose between 1-10% of their body weight, and just 13% lose more than 10%

If youre coming off semaglutide, you can expect an increase in hunger

Manufacturer savings programs exist (Novo Nordisk for semaglutide, Eli Lilly for tirzepatide) but eligibility depends on your insurance and income