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The key regulatory milestones: FDA Breakthrough Therapy designation for MASH (September 2024) EMA PRIME designation for MASH (November 2023) China NMPA Breakthrough designation (June 2024) Phase 3 trials (SYNCHRONIZE-1 and SYNCHRONIZE-2) fully enrolled, results expected H1 of this year Estimated FDA filing: Late this year at the earliest Estimated FDA approval: Possibly next year, depending on Phase 3 results If Phase 3 results confirm Phase 2 findings, survodutide could reach the market within the next 12-24 months

TB-500 is commonly described as a synthetic fragment related to thymosin beta-4, a naturally occurring amino-acid peptide found in many human cells

This keeps the conversation grounded in health history, goals, and whether the option is appropriate for the person requesting it

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