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There are concerns about the generalizability of the clinical data to pediatric patients, given that the average maintenance dose in pediatric patients in Study 023 (| || || || || || || || || || 11 ) exceeded the maximum recommended dose of 2 mg daily

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Pharmaceutical Formulations: In the pharmaceutical sector, L-Cystine is incorporated into formulations for treating conditions related to cysteine deficiency, such as certain metabolic disorders, offering a targeted approach to patient care

Interestingly, vagal CCK signaling is potentiated by vagal leptin signaling 266,267 , and diet-induced leptin resistance in VANs mediates impairments in vagal CCK action 268