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On average, comparative studies show greater weight loss with Mounjaro due to its dual-hormone mechanism, though individual response varies and only a physician can advise on your specific case

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These results underscore Retatrutide's significant potential as a therapy that can meaningfully support weight loss in individuals with obesity." % Average body weight reduction after treatment

Similarly, humans have little, if any, GLP-1R expression in the thyroid (85)

Reddit threads and TikToks mention fatigue, almost a flu-like feeling, intense pain at the injection site, rapid heart rate, and poor circulation in the hands and feet, all of whichso the internet saysoccur within 10 minutes of taking the peptide and remain the most intense for one to two hours