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179 HSP60 and HSP70 in mitochondrial control, stress adaptation, and immune modulation HSP60 plays dual role in tumor promotion and suppression HSP60 exhibits context-dependent roles in cancer, acting as either a tumor promoter or suppressor depending on the malignancy type

The inhibition of ferroptosis can be achieved by targeting the methylation modifications of different histone sites

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It was demonstrated that SiO 2 NPs induced the lung alveolar epithelial cell apoptosis by ROS-regulated PI3K/AKT-mediated mitochondria- and ER stress-dependent signaling pathways, leading to lung injury (Lee et al., 2020)