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Stop taking your GLP-1 medication as soon as severe abdominal pain developsdo not wait for a scheduled appointment or attempt to manage symptoms at home with over-the-counter remedies

Though stimulants like Vyvanse can sometimes be used off-label for conditions like extreme tiredness or cognitive challenges in neurological disorders, Vyvanse might be less likely to be used this way than other stimulants because of how it is metabolized

Step 2: Consult your clinical team

Clinical trial data for semaglutide have not identified mood elevation or depression as common adverse effects

While tirzepatide can be stopped abruptly without medical risk from the medication itself, a thoughtful discontinuation strategy optimizes safety and long-term outcomes