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2 The canonical Wnt pathway, also known as the Wnt/-catenin pathway, involves the nuclear translocation of -catenin and activation of target genes via TCF/LEF transcription factors

These studies consistently demonstrate measurable reductions in fine wrinkles, improvement in mottled hyperpigmentation, increased dermal collagen (confirmed on biopsy), and smoother skin texture over 24 to 48 weeks of use

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The preservation of hair follicles in burn studies has particular relevance for scar quality

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