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If gallstones or inflammation of the gallbladder is suspected, further studies are needed

The internalization of NPs is influenced by several factors, including their composition, size, shape, stiffness, and surface chemistry [73]

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The xenobiotic adaptation in arthropods evolves through multiple mechanisms (Figure 1) [13, 14], including reduced penetration through the cuticle, behavioral avoidance [15, 16], microbiome-mediated detoxification [17-20], enhanced metabolic detoxification [21-25], enhanced sequestration or excretion [13, 19, 26, 27], and target site insensitivity [28-32]