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While the primary goal of GA-1 treatment is protecting the brain during early childhood, researchers and doctors are increasingly recognizing that the kidneys can experience wear and tear over time

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In contrast, a meta-analysis that used less stringent selection criteria included 17 small trials and found evidence of a blood pressure-lowering effect of coenzyme Q 10 in patients with cardiovascular disease or metabolic disorders (48)

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Randomized controlled trials (RCTs), which is the gold-standard approach to extend indication of marketed drugs, have been limited by short follow-up periods and insufficient number of cases to detect the effect of GLP-1R agonists on ovarian cancer 15,16,17