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While efficacy matters, the tolerability and adverse effect profile often determines whether a treatment is suitable for long-term use

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Concerning symptoms Even if you started a vitamin on your own, or with very basic guidance, you should always talk with your provider and expect lab testing to be discussed if you notice: Unexplained tiredness that does not improve Numbness, tingling, balance problems or vision changes Significant mood changes or confusion Frequent fractures or bone pain Unintentional weight loss, ongoing digestive issues or chronic diarrhea These can have many possible causes

I can trace my symptoms back over 40 years though as you say - they did rather snow ball in the last few years

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