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Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice
Zhu KQ, Zhang SJ (2003) Involvement of ATM/ATR-p38 MAPK cascade in MNNG induced G1-S arrest
promoted cardiomyocyte survival (PMID: 25015963) Wound Healing: Accelerated wound closure, reduced scarring in dermal wound models (PMID: 25015963, PMID: 27450738) Corneal: Enhanced corneal epithelial healing
Both activate GLP-1 receptors, and combining them increases side effect risk, particularly nausea and vomiting, without providing additional benefit
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