The peptide undergoes rapid first-pass metabolism when absorbed, which is why bioavailability varies significantly by administration route
The breakdown of oral glutathione in the gut is driven partly by the enzyme gamma-glutamyltransferase, which is why a conventional tablet raises blood glutathione only slightly (Buonocore et al., Oxidative Medicine and Cellular Longevity 2016, PMID 26649136)
Adding more BAC water does not fix this the issue is pH, not volume
That matters because oxidative stress can affect how well the body maintains balance, energy, and overall metabolic health
Its anxiolytic effects are also practically relevant, since chronic neuropathy pain frequently coexists with anxiety and sleep disruption, both of which impair healing