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It was derived from GHRP-1 and incorporates non-natural amino acid substitutions specifically D-2-naphthylalanine (D-2-Nal) and alpha-aminoisobutyric acid (Aib) that confer resistance to enzymatic degradation while optimizing binding affinity at its target receptor

Drugmakers including Pfizer and Roche, as well as smaller companies like Structure Therapeutics, Terns Pharmaceuticals and Viking Therapeutics, also have oral weight-loss drugs in earlier stages of development, BMO research shows

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The recommendations differ substantially between the DAC and non-DAC versions

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