Injection is much more comfortable if combined with B12 as this dilutes the concentration
A second argument in favour of direct stimulation of upper-gut L-cells is the observation that the release of GIP is closely related to that of GLP-1, even at an intra-individual level, indicating that some individuals have a poor response of GIP and GLP-1, and others have average or higher release of both incretin hormones [20]
Behavioral Support: By reducing hunger and cravings, GLP-1 medications can make it easier to adhere to a calorie-restricted diet or a specific eating plan like low-carb, contributing to long-term success
LaFata et al., 2025) and such a pattern of food-intake behavior closely mirrors the compulsive consumption observed in drug addiction, where people are unable to abstain or moderate usage despite recognizing the associated risks (DSM-V, 2013)
These include energy balance, food intake, fever and inflammatory effects, social and sexual function, cognition, cardiovascular effects, nerve creation, neuroprotection, and more (2)