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10.1007/s12272-019-01164-7 182 ParkJ.HwangS.KangY.JungJ.-S.ParkS.HongJ.et al (2019b)

37,38 Biofilms both physically prevent drugs from reaching all cells and induce stress responses, such as the production of enzymes that neutralize drugs

The effects might be additive, synergistic, or potentially counteractive depending on specific circumstances

Role of interleukin-6 in lung complications in patients with COVID-19: therapeutic implications

Therefore, nutraceutical skin applications using collagen and antioxidants such as curcumin and glutathione demonstrate hopeful results for dermal antiaging effects, especially in estrogen-deficient skin