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At 104 weeks, UACR was reduced by 12% in the placebo group and by 40% in the semaglutide group

Because the drug's mechanism of action involves the kidneys, empagliflozin is not advisable for patients with end-stage renal disease, severe renal impairment, or those undergoing dialysis

For danuglipron, most AE were mild in severity at the phase 2 trial for people with T2D, but 2234% of participants receiving the higher doses (80 mg twice daily) discontinued the medication due to AE (vs

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