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These products typically contain dietary ingredients like berberine, green tea extract, curcumin or ashwagandha, which have long been found in other supplements before the rising popularity of GLP-1 agonists

Specifically, in a prospective cohort study, l-carnitine was associated with higher risk of prevalent coronary artery disease, peripheral artery disease, and overall CVD, possibly mediated by its intestinal metabolite, TMAO [5]

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