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GLP-1 agonists for weight loss: pharmacology and clinical implications

Experiments with fasted and calorie-restricted rats showed increased mRNA concentrations of acyl-CoA and CPT-1 in the liver, heart and kidneys compared to control animals due to upregulation of PPAR [111]

Theres also interest in its anti-aging benefits, since boosting NAD+ and improving metabolism can have broad positive effects on health

Furthermore, it has been widely studied in chronic obstructive pulmonary disease (COPD), neurodegenerative diseases, contrast agentinduced nephropathy, and so on [105]

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