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Previous research has shown that GLP1 (936) can decrease levels of IL-1 , interleukin 6 (IL-6), and tumor necrosis factor- (TNF-)

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Key approaches include: Caloric awareness : Maintaining a modest caloric deficit (200300 kcal below maintenance) or at minimum, precise caloric balance Protein prioritization : Consuming 1.21.6 g/kg body weight daily to preserve lean mass and enhance satiety (with appropriate modifications for those with chronic kidney disease or other conditions requiring protein restriction) Volumetric eating : Emphasizing high-fiber, low-energy-density foods (vegetables, fruits, whole grains) that promote fullness Meal structure : Regular eating patterns with planned meals and snacks to prevent impulsive consumption Physical activity intensification becomes critical post-discontinuation