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Despite efforts were made to mitigate misclassification bias and residual confounding through positive and negative controls and the computation of E-values, these risks cannot be completely disregarded

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A common mutation in the 5,10-methylenetetra- hydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status

This approach is determined on a case-by-case basis

However, some findings have demonstrated that NRF2 positively regulates other pathways to induce ferroptosis