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BPC-157 studies listed on PubMed consistently show positive results

Compared with the control group, the treated mice showed a 35% decrease in white adipose tissue mass and markedly reduced adipocyte size

Injecting on Fridays gives you the same four doses but your last injection happens the day before expiration with zero margin

Either is fine but just know that some people do experience insomnia if they take NAD too late at night, but everyone's body is different and your mileage may vary