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CAN is characterized by damage to the nerve fibers that innervate the heart and blood vessels, leading to reduced heart rate variability (variability in the time interval between heartbeats) and increased risk of mortality (80)

Nutritional therapies for hypertension prevention include reducing salt intake, limiting alcohol use, increasing potassium intake, and adopting a general healthy pattern like the DASH or Mediterranean diet (223)

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The residue was diluted with ethyl acetate (100 mL) and deionized water (200 mL)