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Additionally, mRNA expression levels of RUNX-2 and ALP, two key osteogenic markers, were found to be 1.6- and 1.8-fold higher, respectively, in differentiated cells compared to undifferentiated controls

This lack of regulation is a significant concern

Oxidative stress in the context of copper-induced cell toxicity [3, 4] has been linked with the Fenton and Haber-Weiss reactions due to the production of free radicals in conjugation with H 2 O 2 [13]

Researchers have observed upregulation of growth hormone receptor expression in tendon fibroblast cell lines a finding that has generated further mechanistic inquiry

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