Elucidating these mechanisms is pivotal in identifying potential therapeutic interventions, aiming to enhance patient outcomes amidst the complexities of this disorder
Traditional techniques, such as one-hot encoding (OHE), face limitations, particularly in managing high-dimensional data
Dahl JA, Jung I, Aanes H, et al
Importantly, these phase-dependent metabolic responses do not occur in isolation but are modulated by interacting physiological systems, including inflammation, the gut microbiota, circadian rhythms, physical activity, and behavioral factors [9,10,11,12,13,14]
Acknowledgments We thank Gabriela Furlan, Noelia Maldonado and Alejandra Romero (Cell Culture Facility, Luciana Reyna (Molecular Biology Facility), Paula Abadie and Santiago Boccardo (Cytometry Facility), Pilar Crespo (Microscopy Facility), Victoria Blanco and Raul Villarreal (Animal Care Facility), Sergio Oms, Ariel Frontera, Diego Luti, Walter Requena, Cecilia Noriega, and German Romero (BIOPROAL - Animal Production Facility) for their skillful technical assistance at the CIBICI-CONICET/ Department of Clinical Biochemistry, School of Chemistry Sciences, National University of Cordoba