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Histologic Findings: Although any of the features of cutaneous malignancy can be found, most oral melanomas have characteristics of the acral lentiginous (mucosal lentiginous) and, occasionally, superficial spreading types

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Advantages Over Oral and Injectable Routes Direct Buccal Absorption Enters blood vessels through the cheekbypassing stomach acid, digestive enzymes, and first-pass liver metabolism that reduce oral pill bioavailability