Rapid weight loss, particularly when combined with insufficient protein intake, can result in the breakdown of muscle mass

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BET bromodomain inhibition triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors through Bim induction
We employed diamide, an established thiol-oxidizing agent that oxidizes GSH to GS-SG [22], to induce GSR-mediated NADPH consumption during reduction of GS-SG back to GSH (Fig 1A)
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