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Iron and copper: critical executioners of ferroptosis, cuproptosis and other forms of cell death
1975 as cited in ATSDR 2005 Rabinowitz et al
Its been studied more extensively than most growth hormone secretagogues because it received FDA approval for visceral fat reduction in HIV-associated lipodystrophy, which means it has a well-documented safety and efficacy profile in humans
We propose that trimetazidine is a promising drug that can be repurposed to target mitochondrial dysfunction, inflammation and oxidative stress to treat bipolar depression
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