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Melatonin activates two of the G-protein-coupled receptors: MT1 that regulates vigilance states of rapid eye movement (REMS), and MT2 that controls non-REMS

The effects of smaller PET NPs (mean diameter 83 nm) on brain tissue (cerebrum, cerebellum, hippocampus) were investigated in Swiss albino mice after 30-day oral gavage exposure (200 mg/kg/day)

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But, the effectiveness of the treatment depends on a larger parameter

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