Oral Minoxidil is FDA-approved for hypertension but is prescribed off-label for hair concerns at lower doses
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On the other hand, the inhibition of Nrf2 signaling might be employed to enhance the sensitization of chemoresistant tumors to cytotoxic agents, and in this context, it has recently been reported that brusatol, a compound found in a plant extract, acts as inhibitor of this pathway and may exhibit therapeutic utility [111]
Front Mol Neurosci 10:367 Xie X et al (2022) Targeting iron metabolism using gallium nanoparticles to suppress ferroptosis and effectively mitigate acute kidney injury