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PLoS Biol 6 : e22

8 A case-control study that compared 25,956 patients who had vitamin B 12 deficiency with 184,199 control patients found a significantly increased risk of vitamin B 12 deficiency in patients who had taken proton pump inhibitors (odds ratio = 1.65) or histamine H 2 blockers (odds ratio = 1.25) for at least two years

It's also a good option if you need a quick and effective boost in your B12 levels, especially if oral supplements arent doing the trick

Here is one example research week for the 10 mg vial at 150 mcg (45 units), dosed in the morning