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While EGFR family members can compensate IGF-IR inhibition and confer resistance to IGF-IR-targeted agents, IGF-IR can confer resistance to EGFR/ErbB2/ErbB3-targeted therapies as well

Finally, while advising athletes on how to best manage their blood sugar, the doctor needs to be mindful of the potential hyperglycemic response of both high intensity interval training (HIIT) and more strenuous resistance exercise