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A phase 2, 16-week, open-label study in 18 subjects ranging from 6 to 40 years of age results in a mean BMI reduction of 18% in those younger than 18 years, and 6% for those 18 years or older, accompanied by significant reduction of hunger scores ( Figure 4 depicts outcomes for therapies in special populations, such as those with genetic obesity, Prader-Willi Syndrome (PWS), and HO
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Hormonal changes triggering androgenic patterns Fat tissue is not inert
Untreated hypothyroidism can raise cholesterol by 20-50 mg/dL and increase heart disease risk, while severe hyperthyroidism may trigger life-threatening thyroid storm with heart rates exceeding 140 bpm
Since chronic inflammation is an aggravating factor in most tissue injuries, the presence of KPV aims to create an optimal anti-inflammatory environment for repair
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