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Likewise, Fab 3F52 was unable to inhibit compound 2-mediated activation of GLP-1R, suggesting that binding of Fab 3F52 to GLP-1R does not lead to a general stabilization of GLP-1R in an in-active conformation

Like any medication, some patients may experience side effects, typically mild gastrointestinal issues that subside over time

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Sources: MHRA/EMC Wegovy SmPC, NICE TA875 (Semaglutide for managing overweight and obesity), NHS medicines information

Leveraging artificial intelligence and machine learning for characterizing protein corona, nanobiological interactions, and advancing drug discovery