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Patients treated with orforglipron showed an average of 1.3% to 1.6% lower A1C compared with a baseline of 8.0%

"I remember telling my husband, this is what it felt like to be old ," she said

At the start of the study, the TruDiagnostic team and their academic partners took initial blood samples from 184 participants with HIV-associated lipohypertrophy, a condition that results in excess fat and rapid cellular aging, to measure their biological ages

Only semaglutide, tirzepatide, and liraglutide are FDA approved for weight loss, but all of these medications are approved to treat type 2 diabetes

In addition to its effects on insulin and glucagon, GLP-1 slows gastric emptying, promoting feelings of fullness and satiety, which may support healthy weight management goals